Multiple sclerosis and vitamin D a review and recommendations.
A relationship between vitamin D and several diseases, including multiple sclerosis (MS), has recently received interest in the scientific community. Vitamin D appears to have important actions beyond endocrine function, particularly for the immune system. Risk of development of MS, as well as disease severity, has been associated with vitamin D in a variety of studies. There remains a need for prospective studies to further establish this relationship. Given the current evidence of the potential benefits of vitamin D, it appears to be reasonable and safe to consider vitamin D supplementation at dosing adequate to achieve normal levels in patients with MS and clinically isolated syndrome.
Department of Neurology, Oregon Health Science University, 3181 Southwest Sam Jackson Park Road, CR 120, Portland, OR 97239, USA. solomoan@ohsu.edu
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