Thursday 11 August 2011

Vitamin D And Transporter Proteins Hold Key To Prevent Alzheimer’s Disease

Written by Anne Hudsmith

As we grow older our chances of developing Alzheimer’s disease increase. This is attributed to the possible accumulation of a peptide amyloid beta in the brain.

New research has shown that vitamin D is responsible for flushing out amyloid beta from the brain in addition to age-related alteration in the production of transporter proteins which move amyloid beta in and out of the brain. The research was published in BioMed Central‘s open access journal Fluids and Barriers of the CNS.

Age-related decline in memory and cognition, and Alzheimer’s disease have all been linked to low levels of vitamin D in the body. Scientists from Tohoku University, Japan, have conducted research to understand the underlying mechanism and found that injections of vitamin D resulted in better removal of amyloid beta from the brain of mice.

Prof Tetsuya Terasaki said:

“Vitamin D appears to increase transport of amyloid beta across the blood brain barrier (BBB) by regulating protein expression, via the vitamin D receptor, and also by regulating cell signaling via the MEK pathway. These results lead the way towards new therapeutic targets in the search for prevention of Alzheimer’s disease.”

This is a major breakthrough read the full article at Medical News Today

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